Endocrine

DM dx

Random bm > 11.1

Fasting bm > 7

Hba1c > 48

Predm hab1c 42 to 47

ONE READING ISN'T ENOUGH

REMEMBER - fructosamine

Metformin: sucks sugar out of bloodstream into liver, muscle and fat; good for your heart.
Gliclazide: kicks your pancreas to make more insulin; therefore, watch out for hypos.
Gliptin: blocks DPP4, allow incretins to work
GLP1s: mimic the action of incretins.
Gliflozin: makes you pee out excess sugar.
Pioglitazone: makes cells more sensitive to insulin
Insulin: weight gain common.

Incretins produced in the gut on eating; stimulate insulin, delay gastric emptying, and increase satiety

Dm mx -

1st line is metformin or metformin plus gliflozins (if cv risk high for dual theory)

2nd line

met's mates - gliclazide, gliptin (sitagliptin), gliflozin

use because you choose - insulin, pio, glp1 (exatanide, mountjaro)